If I lay here, if I just lay here, would you lie with me and just forget the world?
- Snow Patrol
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itryreallyfuckinghard:mikmikmik
smoking backwards
caught in a landslide, no escape from realityy
(Source: abstractmachines)
DON’T PANIC
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Sembreak: 6 things to do when the day comes.
1. wake up.
2. surf the net. (blog all day)
3. anime marathon.
4. survive the whole day.
5. search for old school musics and maybe some new.
6. wait until evening then off to bed again.
specially made camera.
(Source: 9gag)
![Alzheimer’s Brain Alzheimer’s disease is characterized by neurodegeneration (death of neurons) and the appearance of amyloid beta plaques and tau neurofibrillary tangles thought to cause the neurodegeneration (for more info, go here). This leads to a variety of cognitive problems- perhaps the most well known is memory loss, but there is also severe cognitive decline (inability to do simple tasks, such as draw a straight line, connect the dots, etc.). This side by side comparison of an Alzheimer’s brain with a healthy brain really helps to illustrate the severe neurodegeneration that occurs. The ventricles seem to become bigger (due to loss of the brain tissue that would normally surround them), gray matter decreases a lot- the cell bodies of neurons are dying, and this is what really causes the cognitive decline- for motor tasks, simple thinking tasks, etc. You can really see how much of the gray matter has disappeared in the above image. Additionally, the hippocampus (read more about hippocampus here) is almost entirely dead and gone. The hippocampus is that squiggly thing on the bottom center (on the inside of the section that loops down on the side) that is a hole in the Alzheimer’s brain. You can see how it kind of resembles the rodent hippocampus in the linked post above. Hippocampus, which is responsible for memory storage, creation, and some retrieval, really cannot work well when it has degenerated in Alzheimer’s, and it is one of the first places to experience degeneration, which is why memory loss is one of the first symptoms. [Image Source]](http://28.media.tumblr.com/tumblr_l42nqtw2rz1qb6etto1_400.jpg)
Alzheimer’s Brain
Alzheimer’s disease is characterized by neurodegeneration (death of neurons) and the appearance of amyloid beta plaques and tau neurofibrillary tangles thought to cause the neurodegeneration (for more info, go here). This leads to a variety of cognitive problems- perhaps the most well known is memory loss, but there is also severe cognitive decline (inability to do simple tasks, such as draw a straight line, connect the dots, etc.).
This side by side comparison of an Alzheimer’s brain with a healthy brain really helps to illustrate the severe neurodegeneration that occurs. The ventricles seem to become bigger (due to loss of the brain tissue that would normally surround them), gray matter decreases a lot- the cell bodies of neurons are dying, and this is what really causes the cognitive decline- for motor tasks, simple thinking tasks, etc. You can really see how much of the gray matter has disappeared in the above image. Additionally, the hippocampus is almost entirely dead and gone. The hippocampus is that squiggly thing on the bottom center (on the inside of the section that loops down on the side) that is a hole in the Alzheimer’s brain. You can see how it kind of resembles the rodent hippocampus in the linked post above. Hippocampus, which is responsible for memory storage, creation, and some retrieval, really cannot work well when it has degenerated in Alzheimer’s, and it is one of the first places to experience degeneration, which is why memory loss is one of the first symptoms.
Lights Out: Epic trollface is epic.